Launch of Scoundrel'
Louis Bartos' boat Scoundrel was
photographed as it was being launched at Bar Harbor Tuesday with
the crew of Carl Thompson and Tom Thompson, Jack and Bev Davies
and Jim and Mary Lynne Dahl - and of course Louis Bartos, The
Front Page Photo by Jim Dahl - More...
the battle of the bulge: We're a scrimmage closer to victory;
New Saint Louis University research sheds light on how obesity
occurs - Saint Louis University researchers believe they've
won a major skirmish in the battle of the bulge, and their findings
are published in the May issue of Diabetes.
"We figured out how obesity
occurs," says William A. Banks, M.D., professor of geriatrics
in the department of internal medicine and professor of pharmacological
and physiological science at Saint Louis University School of
Medicine. "The next step is coming up with the solution."
The scientists used mice to
look at how leptin, a hormone secreted by fat cells that tells
us to stop eating, gets into the brain. They found that in obese
mice, high triglycerides, a type of fat in the bloodstream, prevents
leptin from getting into the brain, where it can do its work
in turning off feeding and burning calories.
"High triglycerides are
blocking the leptin from getting into the brain. If leptin can't
get into the brain, it can't tell you to stop eating," says
Banks, who is principal investigator and a staff physician at
Veterans Affairs Medical Center in St. Louis.
"This is a big deal. We
now know what is keeping leptin from getting to where it needs
to do its work."
Paradoxically high triglycerides
occur in both fat and starving animals and make the brain think
the body's starving so the animal keeps eating, which makes it
gain more weight. - Read
Wednesday - April 28, 2004